In 2009, Munoz turned professional in September and finished fifth at the LPGA Final Qualifying Tournament, where she earned Priority List Category 11 for the 2010 LPGA season. She also competed on the Ladies European Tour (LET), and managed to win the Madrid Masters on the first playoff hole, defeating former ASU teammate Anna Nordqvist with an eagle putt.

In 2010, her best finish was tied for fourth at the Bell Micro LPGA Classic. She was also named the LPGA Rookie of the Year.

Came tied 8th in the Kraft Nabisco Championship; tied 45th in the Women抯 US Championship 2011.  Azahara won over $500,000 in 2011, 24th on the world抯 money list.

Munoz captured her first tour title in 2012 at The Sybase Match Play Championship. She also crossed the $2 million mark in career earnings and made 22 cuts including 9 top 10 finishes.