LPGA Tour events in each of ten seasons. She met this criterion on 9 June 2005 when she completed the first round of the LPGA Championship. At age 30, she became the youngest living person ever to enter the Hall of Fame, and kept that distinction until 2007, when fellow LPGA star Se Ri Pak was inducted.
Webb staged a comeback season in 2006. In the final round at the Kraft Nabisco Championship she holed a 116-yard shot from the fairway to eagle the 18th hole and then birdied the same hole in a sudden-death playoff to beat Lorena Ochoa and win her second Kraft Nabisco Championship. She won four other tournaments including the Evian Masters and Mizuno Classic. Her 2006 Kraft Nabisco win took her into the top ten of the Women's World Golf Rankings for the first time since they were introduced in February 2006.
Her 36 LPGA Tour victories places her twelfth on the list of players with the most career LPGA tournament wins.
In 2007, her best finish was runner-up at the McDonald's LPGA Championship Presented by Coca-Cola and recorded five additional top-10 finishes. She also won her seventh and eighth career international victories at the MFS Women’s Australian Open and the ANZ Ladies Masters (sixth time) on the ALPG Tour.
In 2008, Webb’s best finish was runner-up at the Ginn Tribute Hosted by ANNIKA, where she lost to Seon Hwa Lee in a one-hole,sudden-death playoff; also posted a runner-up finish at the season-ending ADT Championship. She managed to cross the $14 million mark in career earnings with a fifth-place finish at the Jamie Farr Owens Corning Classic Presented by Kroger. She also won the MFS Women's Australian Open on the Australian Ladies Professional Golf (ALPG) Tour for the third time in her career, which was her ninth international victory.
In 2009, she won the J Golf Phoenix LPGA International Presented by Mirassou Winery, her 36th victory on the LPGA Tour and recorded runner-up finishes at both the RICOH Women's British Open, her season-best finish at a major championship and at the CN Canadian Women's Open.
In 2010, Webb earned her 10th international victory at the Australian Ladies Masters - an Australian Ladies Professional Golf (ALPG) and Ladies European Tour (LET) co-sanctioned event. Her other strong performance of the season was when she finished tied for fourth place at the season-opening Honda PTT LPGA Thailand. She also managed to tie for fifth at the Kraft Nabisco Championship and LPGA Championship Presented by Wegmans.
2011 saw Webb record back-to-back victories at the HSBC Women's Champions and RR Donnelley LPGA Founders Cup. In 2012 and for the second time in her career Webb posted back-to-back seasons without a missed cut (1999-2000). This included her finishing T-2 at the Evian Masters.