In 2008, Stanford recorded her second and third LPGA career victories at the Bell Micro LPGA Classic and the inaugural Lorena Ochoa Invitational by Banamex and Corona Light, where she crossed the $1 million mark in season earnings; she carded a career-low 62 in the opening round of the Safeway International Presented by Coca-Cola, which was also the lowest first round score on Tour in 2008; crossed the $3 million mark in career earnings at the SemGroup Championship Presented by John Q. Hammons, where she tied for third; she also recorded six of her season's 10 top-10 finishes in her final six events of the year.

In 2009, Stanford won the season-opening SBS Open at Turtle Bay, where she crossed the $4 million mark in career earnings and recorded a season-low 65 in the opening round; she tied for second at the CN Canadian Women's Open, where she carded a season-low 65 in the second round, and the P&G Beauty NW Arkansas Championship presented by John Q. Hammons, where she lost a three-way (with Sun Young Yoo) sudden-death playoff to Jiyai Shin; Stanford earned $143,063 and crossed the $1 million milestone in season earnings for the second year in a row; added eight additional top 10 finishes; qualified for her third U.S. Solheim Cup Team, posting a 1-2-1 record for the victorious U.S. Team; led the Tour lead in eagles with 13. 

Angela Stanford抯 best finish in 2010 came at the Sybase Match Play Championship where she placed runner-up, losing 3&1 to Sun Young Yoo. She also managed five other top 10 finishes in the season.

In 2011 Angela finished tied 3rd at the Kraft Nabisco Championship. She also finished tied 22nd in the Women抯 Open Championship played at Carnoustie, Scotland. In the Women抯 US Open she finished 4th in 2011. Became 7th in the World Money List.

Stanford recorded her fifth-career victory at the HSBC Women抯 Champions 2012 whilst also having 6 top 10 finishes. She also won the inaugural Kia Community Assist Award for her work with the Angela Stanford Foundation.