In 2008, Yang recorded a season-best tie for ninth at the Hana Bank Kolon Championship 2008; competed on the Ladies European Tour (LET), winning the HypoVereinsbank Ladies German Open presented by Audi and the Scandinavian TPC hosted by Annika. Carded eight additional top-10 finishes and ended the year ranked fourth on the LET New Star Money List; returned to the LPGA Final Qualifying Tournament, where she finished runner-up to earn Priority List Category 11 for the 2009 LPGA season.
In 2009, Amy Yang recorded a career-best tie for third at the CVS/pharmacy LPGA Challenge, where she carded a career-low 66 in the final round; tied for ninth at the McDonald's LPGA Championship Presented by Coca Cola, her best finish at a major championship; carded her first LPGA career hole-in-one during the third round of the LPGA Corning Classic.
In 2010, Yang finished in the top 10 on five occasions, most notably when she finished fourth at the Sybase Match Play Championship. She also tied for fifth at the U.S. Women's Open, the RICOH Women's British Open and the Navistar LPGA Classic Presented by Monaco.
In 2011, she recorded seven top-10 finishes including: second at the Walmart NW Arkansas Championship where she lost in a playoff to Yani Tseng; tied for second at the Sunrise LPGA Taiwan Championship; fourth at the RICOH Women's British Open; tied for sixth at the Avnet LPGA Classic; seventh at the Honda LPGA Thailand; tied for seventh at the LPGA HanaBank Championship; tied for 10th at the US Women's Open. Won the KB Star Championship on the KLPGA, her third-career international victory.
2012 saw Yang record 5 top 10 finishes including a career best runner up at the US Women's Open.